2lxi: Difference between revisions
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{{STRUCTURE_2lxi| PDB=2lxi | SCENE= }} | {{STRUCTURE_2lxi| PDB=2lxi | SCENE= }} | ||
===NMR structure of the N-terminal RNA Binding domain 1 (RRM1) of the protein RBM10 from Homo sapiens=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2lxi]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LXI OCA]. | [[2lxi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LXI OCA]. | ||
[[Category: Dutta, S.]] | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Dutta, S K.]] | |||
[[Category: Geralt, M.]] | [[Category: Geralt, M.]] | ||
[[Category: JCSG, Joint Center for Structural Genomics.]] | [[Category: JCSG, Joint Center for Structural Genomics.]] | ||
