2w44: Difference between revisions
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{{STRUCTURE_2w44| PDB=2w44 | SCENE= }} | {{STRUCTURE_2w44| PDB=2w44 | SCENE= }} | ||
=== | ===Structure DeltaA1-A4 insulin=== | ||
{{ | {{ABSTRACT_PUBMED_20568733}} | ||
==Function== | ==Function== | ||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[2w44]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W44 OCA]. | [[2w44]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W44 OCA]. | ||
==Reference== | ==Reference== | ||
Revision as of 06:30, 20 June 2013
Structure DeltaA1-A4 insulin
Template:ABSTRACT PUBMED 20568733
Function
[A6XGL2_HUMAN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).[SAAS:SAAS022353_004_028339]
About this Structure
2w44 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Thorsoe KS, Schlein M, Steensgaard DB, Brandt J, Schluckebier G, Naver H. Kinetic evidence for the sequential association of insulin binding sites 1 and 2 to the insulin receptor and the influence of receptor isoform. Biochemistry. 2010 Jul 27;49(29):6234-46. PMID:20568733 doi:10.1021/bi1000118
