4i8v: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[4i8v]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I8V OCA]. | [[4i8v]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I8V OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023508959</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Unspecific monooxygenase]] | [[Category: Unspecific monooxygenase]] | ||
Revision as of 06:38, 20 June 2013
Human Cytochrome P450 1A1 in complex with alpha-naphthoflavone
Template:ABSTRACT PUBMED 23508959
Function
[CP1A1_HUMAN] Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
About this Structure
4i8v is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Walsh AA, Szklarz GD, Scott EE. Human Cytochrome P450 1A1 Structure and Utility In Understanding Drug and Xenobiotic Metabolism. J Biol Chem. 2013 Mar 18. PMID:23508959 doi:10.1074/jbc.M113.452953
