2lqr: Difference between revisions
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{{STRUCTURE_2lqr| PDB=2lqr | SCENE= }} | {{STRUCTURE_2lqr| PDB=2lqr | SCENE= }} | ||
===NMR structure of Ig3 domain of palladin=== | ===NMR structure of Ig3 domain of palladin=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/PALLD_MOUSE PALLD_MOUSE]] Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific May be required for the initiation of neural tube closure.<ref>PMID:10931874</ref> <ref>PMID:15950489</ref> <ref>PMID:16492705</ref> <ref>PMID:17115415</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2lqr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQR OCA]. | [[2lqr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQR OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Beck, M R.]] | [[Category: Beck, M R.]] | ||
