3va0: Difference between revisions
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{{STRUCTURE_3va0| PDB=3va0 | SCENE= }} | {{STRUCTURE_3va0| PDB=3va0 | SCENE= }} | ||
===Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site=== | ===Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site=== | ||
{{ABSTRACT_PUBMED_22718982}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RNT_ECOLI RNT_ECOLI]] Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases.[HAMAP-Rule:MF_00157] | |||
==About this Structure== | ==About this Structure== | ||
[[3va0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3va0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VA0 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022718982</ref><references group="xtra"/> | <ref group="xtra">PMID:022718982</ref><references group="xtra"/><references/> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli k-12]] | ||
[[Category: Hsiao, Y Y.]] | [[Category: Hsiao, Y Y.]] | ||
[[Category: Yuan, H S.]] | [[Category: Yuan, H S.]] | ||
Revision as of 08:10, 30 June 2013
Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site
Template:ABSTRACT PUBMED 22718982
Function
[RNT_ECOLI] Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases.[HAMAP-Rule:MF_00157]
About this Structure
3va0 is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Hsiao YY, Duh Y, Chen YP, Wang YT, Yuan HS. How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes. Nucleic Acids Res. 2012 Jun 19. PMID:22718982 doi:10.1093/nar/gks548