4jbj: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Structural mimicry for functional antagonism===

~~The entry 4jbj is ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/IFI2_MOUSE IFI2_MOUSE]] Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. Binds dsDNA in the cytosol. Is involved in innate immune response and has anti-inflammatory activity. Inhibits caspase activation in response to cytosolic DNA and may inhibit the activation of the AIM2 inflammasome, probably via association with AIM2.<ref>PMID:16670293</ref> <ref>PMID:19131592</ref>

~~Authors~~: ~~Ru, H~~.~~, Ni, X~~.-M.~~, Ma, F., Zhao, L.-X., Ding, W., Hung, L.-W., Shaw, N~~.~~, Cheng, G.-H~~.~~, Liu, Z~~.-J.

==About this Structure==

[[4jbj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JBJ OCA].

~~Description~~: ~~Structural mimicry for functional antagonism~~

==Reference==

[[Category: Mus musculus]]

[[Category: Cheng, G.]]

[[Category: Ding, W.]]

[[Category: Hung, L W.]]

[[Category: Liu, Z J.]]

[[Category: Ma, F.]]

[[Category: Ni, X.]]

[[Category: Ru, H.]]

[[Category: Shaw, N.]]

[[Category: Zhao, L.]]

[[Category: Dna binding protein]]

[[Category: Ds dna]]

[[Category: Ob fold]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4jbj|  PDB=4jbj  |  SCENE=  }}
+===Structural mimicry for functional antagonism===
-The entry 4jbj is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/IFI2_MOUSE IFI2_MOUSE]] Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. Binds dsDNA in the cytosol. Is involved in innate immune response and has anti-inflammatory activity. Inhibits caspase activation in response to cytosolic DNA and may inhibit the activation of the AIM2 inflammasome, probably via association with AIM2.<ref>PMID:16670293</ref> <ref>PMID:19131592</ref>
-Authors: Ru, H., Ni, X.-M., Ma, F., Zhao, L.-X., Ding, W., Hung, L.-W., Shaw, N., Cheng, G.-H., Liu, Z.-J.
+==About this Structure==
+[[4jbj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JBJ OCA].
-Description: Structural mimicry for functional antagonism
+==Reference==
+<ref group="xtra">PMID:023567559</ref><references group="xtra"/><references/>
+[[Category: Mus musculus]]
+[[Category: Cheng, G.]]
+[[Category: Ding, W.]]
+[[Category: Hung, L W.]]
+[[Category: Liu, Z J.]]
+[[Category: Ma, F.]]
+[[Category: Ni, X.]]
+[[Category: Ru, H.]]
+[[Category: Shaw, N.]]
+[[Category: Zhao, L.]]
+[[Category: Dna binding protein]]
+[[Category: Ds dna]]
+[[Category: Ob fold]]