3w1f: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3w1f|  PDB=3w1f  |  SCENE=  }}
===Crystal structure of Human MPS1 catalytic domain in complex with 5-(5-ethoxy-6-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-3-yl)-2-methylbenzenesulfonamide===
{{ABSTRACT_PUBMED_23634759}}


The entry 3w1f is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/TTK_HUMAN TTK_HUMAN]] Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.<ref>PMID:18243099</ref>  


Authors: Kusakabe, K., Ide, N., Daigo, Y., Tachibana, Y., Itoh, T., Yamamoto, T., Hashizume, H., Hato, Y., Higashino, K., Okano, Y., Sato, Y., Inoue, M., Iguchi, M., Kanazawa, T., Ishioka, Y., Dohi, K., Kido, Y., Sakamoto, S., Yasuo, K., Maeda, M., Higaki, M., Ueda, K., Yoshizawa, H., Baba, Y., Shiota, T., Murai, H., Nakamura, Y.
==About this Structure==
[[3w1f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W1F OCA].  


Description: CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 5-(5-ethoxy-6-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-3-yl)-2-methylbenzenesulfonamide
==Reference==
<ref group="xtra">PMID:023634759</ref><references group="xtra"/><references/>
[[Category: Dual-specificity kinase]]
[[Category: Homo sapiens]]
[[Category: Baba, Y.]]
[[Category: Daigo, Y.]]
[[Category: Dohi, K.]]
[[Category: Hashizume, H.]]
[[Category: Hato, Y.]]
[[Category: Higaki, M.]]
[[Category: Higashino, K.]]
[[Category: Ide, N.]]
[[Category: Iguchi, M.]]
[[Category: Inoue, M.]]
[[Category: Ishioka, Y.]]
[[Category: Itoh, T.]]
[[Category: Kanazawa, T.]]
[[Category: Kido, Y.]]
[[Category: Kusakabe, K.]]
[[Category: Maeda, M.]]
[[Category: Murai, H.]]
[[Category: Nakamura, Y.]]
[[Category: Okano, Y.]]
[[Category: Sakamoto, S.]]
[[Category: Sato, Y.]]
[[Category: Shiota, T.]]
[[Category: Tachibana, Y.]]
[[Category: Ueda, K.]]
[[Category: Yamamoto, T.]]
[[Category: Yasuo, K.]]
[[Category: Yoshizawa, H.]]
[[Category: Kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/3w1f"