4awa: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4awa|  PDB=4awa  |  SCENE=  }}
===Crystal structure of active legumain in complex with YVAD-CMK at pH 5.0===
{{ABSTRACT_PUBMED_23776206}}


The entry 4awa is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/LGMN_HUMAN LGMN_HUMAN]] Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.


Authors: Dall, E., Brandstetter, H.
==About this Structure==
[[4awa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AWA OCA].  


Description: Crystal structure of active legumain in complex with YVAD-CMK at pH 5. 0
==Reference==
<ref group="xtra">PMID:023776206</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Legumain]]
[[Category: Brandstetter, H.]]
[[Category: Dall, E.]]
[[Category: Aep]]
[[Category: Antigen processing]]
[[Category: Cancer]]
[[Category: Cysteine protease]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Lysosomal]]
[[Category: Mhcii]]
[[Category: Substrate specificity]]