4fzj: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4fzj|  PDB=4fzj  |  SCENE=  }}
===Pantothenate synthetase in complex with 1,3-DIMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID===


The entry 4fzj is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref>  


Authors: Silvestre, H.L., Blundell, T.L., Abell, C., Ciulli, A.
==About this Structure==
[[4fzj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FZJ OCA].  


Description: Pantothenate synthetase in complex with fragment 8
==Reference==
<references group="xtra"/><references/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Abell, C.]]
[[Category: Blundell, T L.]]
[[Category: Ciulli, A.]]
[[Category: Silvestre, H L.]]
[[Category: Citoplasm]]
[[Category: Ligase]]
[[Category: Rossmann fold]]

Revision as of 10:25, 30 June 2013

Template:STRUCTURE 4fzj

Pantothenate synthetase in complex with 1,3-DIMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID

Function

[PANC_MYCTU] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[1]

About this Structure

4fzj is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. ↑ Zheng R, Blanchard JS. Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase. Biochemistry. 2001 Oct 30;40(43):12904-12. PMID:11669627

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