3w0d: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3w0d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_fumigatus_af293 Aspergillus fumigatus af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0D OCA]. | [[3w0d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_fumigatus_af293 Aspergillus fumigatus af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0D OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023640894</ref><references group="xtra"/><references/> | |||
[[Category: Aspergillus fumigatus af293]] | [[Category: Aspergillus fumigatus af293]] | ||
[[Category: Homma, M.]] | [[Category: Homma, M.]] | ||
Revision as of 09:03, 3 July 2013
Structure of elastase inhibitor AFUEI (cyrstal form I)
Template:ABSTRACT PUBMED 23640894
Function
[IELA_ASPFU] Elastase inhibitor. Non-competitive inhibitor of A.fumigatus elastase with a Ki of 1.6 nM. Inhibits the fibrinogenase and collagenase activities of A.fumigatus elastase. Inhibitor of A.flavus elastase and human leukocyte elastase, and weakly inhibits porcine pancreatic elastase. Does not inhibit elastase from P.aeruginosa or C.atrox venom.
About this Structure
3w0d is a 2 chain structure with sequence from Aspergillus fumigatus af293. Full crystallographic information is available from OCA.
Reference
- Sakuma M, Imada K, Okumura Y, Uchiya KI, Yamashita N, Ogawa K, Hijikata A, Shirai T, Homma M, Nikai T. X-ray structure analysis and characterization of AFUEI, an elastase inhibitor from Aspergillus fumigatus. J Biol Chem. 2013 May 2. PMID:23640894 doi:10.1074/jbc.M112.433987
