4els: Difference between revisions

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[[Image:4els.jpg|left|200px]]
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{{STRUCTURE_4els|  PDB=4els  |  SCENE=  }}  
{{STRUCTURE_4els|  PDB=4els  |  SCENE=  }}  
===Structure of E. Coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with bicarbonate===
===Structure of E. Coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with bicarbonate===
{{ABSTRACT_PUBMED_22606952}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/MENB_ECOLI MENB_ECOLI]] Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).<ref>PMID:1091286</ref> <ref>PMID:20643650</ref> 
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{{ABSTRACT_PUBMED_22606952}}


==About this Structure==
==About this Structure==
[[4els]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELS OCA].  
[[4els]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELS OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:022606952</ref><references group="xtra"/>
<ref group="xtra">PMID:022606952</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: 1,4-dihydroxy-2-naphthoyl-CoA synthase]]
[[Category: Naphthoate synthase]]
[[Category: Escherichia coli k-12]]
[[Category: Guo, Z H.]]
[[Category: Guo, Z H.]]
[[Category: Jiang, M.]]
[[Category: Jiang, M.]]

Revision as of 10:15, 3 July 2013

Template:STRUCTURE 4els

Structure of E. Coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with bicarbonate

Template:ABSTRACT PUBMED 22606952

Function

[MENB_ECOLI] Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).[1] [2]

About this Structure

4els is a 6 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  1. Sun Y, Song H, Li J, Jiang M, Li Y, Zhou J, Guo Z. Active Site Binding and Catalytic Role of Bicarbonate in 1,4-Dihydroxy-2-naphthoyl Coenzyme A Synthases from Vitamin K Biosynthetic Pathways. Biochemistry. 2012 May 24. PMID:22606952 doi:10.1021/bi300486j
  1. ↑ Young IG. Biosynthesis of bacterial menaquinones. Menaquinone mutants of Escherichia coli. Biochemistry. 1975 Jan 28;14(2):399-406. PMID:1091286
  2. ↑ Jiang M, Chen M, Guo ZF, Guo Z. A bicarbonate cofactor modulates 1,4-dihydroxy-2-naphthoyl-coenzyme a synthase in menaquinone biosynthesis of Escherichia coli. J Biol Chem. 2010 Sep 24;285(39):30159-69. doi: 10.1074/jbc.M110.147702. Epub, 2010 Jul 19. PMID:20643650 doi:10.1074/jbc.M110.147702

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