3g75: Difference between revisions
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{{STRUCTURE_3g75| PDB=3g75 | SCENE= }} | {{STRUCTURE_3g75| PDB=3g75 | SCENE= }} | ||
===Crystal structure of Staphylococcus aureus Gyrase B co-complexed with 4-METHYL-5-[3-(METHYLSULFANYL)-1H-PYRAZOL-5-YL]-2-THIOPHEN-2-YL-1,3-THIAZOLE inhibitor=== | |||
{{ABSTRACT_PUBMED_20356737}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/GYRB_STAAU GYRB_STAAU]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.[HAMAP-Rule:MF_01898] | |||
==About this Structure== | ==About this Structure== | ||
[[3g75]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G75 OCA]. | [[3g75]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G75 OCA]. | ||
== | ==Reference== | ||
<ref group="xtra">PMID:020356737</ref><references group="xtra"/><references/> | |||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
[[Category: Charifson, P.]] | [[Category: Charifson, P.]] | ||
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[[Category: Antibiotic resistance]] | [[Category: Antibiotic resistance]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
[[Category: Isomerase-isomerase inhibitor complex]] | |||
