1f1j: Difference between revisions
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{{STRUCTURE_1f1j| PDB=1f1j | SCENE= }} | {{STRUCTURE_1f1j| PDB=1f1j | SCENE= }} | ||
===CRYSTAL STRUCTURE OF CASPASE-7 IN COMPLEX WITH ACETYL-ASP-GLU-VAL-ASP-CHO=== | ===CRYSTAL STRUCTURE OF CASPASE-7 IN COMPLEX WITH ACETYL-ASP-GLU-VAL-ASP-CHO=== | ||
{{ABSTRACT_PUBMED_10873833}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:010873833</ref><references group="xtra"/> | <ref group="xtra">PMID:010873833</ref><references group="xtra"/><references/> | ||
[[Category: Caspases]] | [[Category: Caspases]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
