3rop: Difference between revisions

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[[Image:3rop.jpg|left|200px]]
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{{STRUCTURE_3rop|  PDB=3rop  |  SCENE=  }}  
{{STRUCTURE_3rop|  PDB=3rop  |  SCENE=  }}  
===Crystal structure of human CD38 in complex with compound CZ-50b===
===Crystal structure of human CD38 in complex with compound CZ-50b===
{{ABSTRACT_PUBMED_22142305}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/CD38_HUMAN CD38_HUMAN]] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.  
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{{ABSTRACT_PUBMED_22142305}}


==About this Structure==
==About this Structure==
[[3rop]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROP OCA].  
[[3rop]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROP OCA].  
==See Also==
*[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]]


==Reference==
==Reference==
<ref group="xtra">PMID:022142305</ref><references group="xtra"/>
<ref group="xtra">PMID:022142305</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hao, Q.]]
[[Category: Hao, Q.]]

Revision as of 12:37, 3 July 2013

Template:STRUCTURE 3rop

Crystal structure of human CD38 in complex with compound CZ-50b

Template:ABSTRACT PUBMED 22142305

Function

[CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

About this Structure

3rop is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Kwong AK, Chen Z, Zhang H, Leung FP, Lam CM, Ting KY, Zhang L, Hao Q, Zhang LH, Lee HC. Catalysis-Based Inhibitors of the Calcium Signaling Function of CD38. Biochemistry. 2011 Dec 14. PMID:22142305 doi:10.1021/bi201509f

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