4gno: Difference between revisions
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{{STRUCTURE_4gno| PDB=4gno | SCENE= }} | |||
===Structure of rat cytosolic PEPCK Ld_3g in complex with Beta-Sulfopyruvate and GTP=== | |||
{{ABSTRACT_PUBMED_23127136}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PCKGC_RAT PCKGC_RAT]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | |||
==About this Structure== | |||
[[4gno]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNO OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023127136</ref><references group="xtra"/><references/> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Holyoak, T.]] | |||
[[Category: Johnson, T A.]] | |||
[[Category: Gluconeogenesis]] | |||
[[Category: Kinase]] | |||
[[Category: Lyase]] | |||
Revision as of 14:09, 3 July 2013
Structure of rat cytosolic PEPCK Ld_3g in complex with Beta-Sulfopyruvate and GTP
Template:ABSTRACT PUBMED 23127136
Function
[PCKGC_RAT] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
About this Structure
4gno is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Johnson TA, Holyoak T. The Omega-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry. 2012 Nov 27;51(47):9547-59. doi: 10.1021/bi301278t. Epub 2012 Nov, 14. PMID:23127136 doi:10.1021/bi301278t