4g5y: Difference between revisions
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{{STRUCTURE_4g5y| PDB=4g5y | SCENE= }} | |||
===Crystal Structure of Mycobacterium tuberculosis Pantothenate synthetase in a ternary complex with ATP and N,N-DIMETHYLTHIOPHENE-3-SULFONAMIDE=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref> | |||
==About this Structure== | |||
[[4g5y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G5Y OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Pantoate--beta-alanine ligase]] | |||
[[Category: Abell, C.]] | |||
[[Category: Blundell, T L.]] | |||
[[Category: Ciulli, A.]] | |||
[[Category: Silvestre, H L.]] | |||
[[Category: Drug design]] | |||
[[Category: Fragment-based]] | |||
[[Category: Ligase]] | |||
[[Category: Ligase-ligase inhibitor complex]] | |||
[[Category: Pantothenate biosynthesis]] | |||