Growth differentiation factor: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='3evs' size='350' side='right' caption='Structure of growth differentiation factor GDF-5 (green) complex with bone morphogenetic receptor (pink) (PDB entry [[3evs]])' scene=''> | <StructureSection load='3evs' size='350' side='right' caption='Structure of growth differentiation factor GDF-5 (green) complex with bone morphogenetic receptor (pink) (PDB entry [[3evs]])' scene=''> | ||
| Line 5: | Line 5: | ||
*'''GDF-2''' maintain the response of cholinergic neurons to acetylcholine.<br /> | *'''GDF-2''' maintain the response of cholinergic neurons to acetylcholine.<br /> | ||
*'''GDF-5''' is expressed in the central nervous system and is involved in the development of joints and skeleton.<br /> | *'''GDF-5''' is expressed in the central nervous system and is involved in the development of joints and skeleton.<br /> | ||
*'''GDF-8''' or myostatin, controls the growth of muscle tissue. For more details see [[Group:MUZIC:Myostatin]]. | *'''GDF-8''' or '''myostatin''', controls the growth of muscle tissue. For more details see [[Group:MUZIC:Myostatin]]. | ||
==3D structures of growth differentiation factor== | ==3D structures of growth differentiation factor== | ||
Revision as of 07:38, 8 July 2013
<StructureSection load='3evs' size='350' side='right' caption='Structure of growth differentiation factor GDF-5 (green) complex with bone morphogenetic receptor (pink) (PDB entry 3evs)' scene=>
Growth differentiation factor (GDF) are proteins which function in development.
- GDF-2 maintain the response of cholinergic neurons to acetylcholine.
- GDF-5 is expressed in the central nervous system and is involved in the development of joints and skeleton.
- GDF-8 or myostatin, controls the growth of muscle tissue. For more details see Group:MUZIC:Myostatin.
3D structures of growth differentiation factor
Updated on 08-July-2013
GDF-2
1zkz – hGDF – human
4fao – hGDF + serine/threonine-protein kinase receptor + activin receptor
GDF-5
2bhk, 1waq – hGDF
3evs – hGDF + bone morphogenetic receptor
3qb4 – hGDF (mutant) + bone morphogenetic receptor
GDF-8
3hh2 – mGDF + follistatin – mouse
3sek – mGDF + follistatin-related protein
