4ij6: Difference between revisions
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{{STRUCTURE_4ij6| PDB=4ij6 | SCENE= }} | |||
===Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from <i>Hydrogenobacter thermophilus</i> TK-6 in Complex with L-phosphoserine=== | |||
{{ABSTRACT_PUBMED_23479726}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PSPA_HYDTT PSPA_HYDTT]] Catalyzes the dephosphorylation of L-phosphoserine to serine and inorganic phosphate. Is poorly or not active toward D-phosphoserine, DL-phosphothreonine, 3-phosphoglycerate, para-nitrophenylphosphate, and fructose-6-phosphate. Does not display phosphoglycerate mutase activity. | |||
==About this Structure== | |||
[[4ij6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenobacter_thermophilus_tk-6 Hydrogenobacter thermophilus tk-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IJ6 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023479726</ref><references group="xtra"/><references/> | |||
[[Category: Hydrogenobacter thermophilus tk-6]] | |||
[[Category: Phosphoserine phosphatase]] | |||
[[Category: Arai, H.]] | |||
[[Category: Chiba, Y.]] | |||
[[Category: Horita, S.]] | |||
[[Category: Igarashi, Y.]] | |||
[[Category: Ishii, M.]] | |||
[[Category: Nagata, K.]] | |||
[[Category: Ohtsuka, J.]] | |||
[[Category: Tanokura, M.]] | |||
[[Category: Hydrolase]] | |||
[[Category: Phosphatase]] | |||
Revision as of 14:04, 10 July 2013
Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from Hydrogenobacter thermophilus TK-6 in Complex with L-phosphoserine
Template:ABSTRACT PUBMED 23479726
Function
[PSPA_HYDTT] Catalyzes the dephosphorylation of L-phosphoserine to serine and inorganic phosphate. Is poorly or not active toward D-phosphoserine, DL-phosphothreonine, 3-phosphoglycerate, para-nitrophenylphosphate, and fructose-6-phosphate. Does not display phosphoglycerate mutase activity.
About this Structure
4ij6 is a 2 chain structure with sequence from Hydrogenobacter thermophilus tk-6. Full crystallographic information is available from OCA.
Reference
- Chiba Y, Horita S, Ohtsuka J, Arai H, Nagata K, Igarashi Y, Tanokura M, Ishii M. Structural units important for activity of a novel-type phosphoserine phosphatase from Hydrogenobacter thermophilus TK-6 revealed by crystal structure analysis. J Biol Chem. 2013 Apr 19;288(16):11448-58. doi: 10.1074/jbc.M112.449561. Epub, 2013 Mar 11. PMID:23479726 doi:10.1074/jbc.M112.449561
