3tz6: Difference between revisions

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[[Image:3tz6.jpg|left|200px]]
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{{STRUCTURE_3tz6|  PDB=3tz6  |  SCENE=  }}  
{{STRUCTURE_3tz6|  PDB=3tz6  |  SCENE=  }}  
===Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With inhibitor SMCS (CYS) And Phosphate From Mycobacterium tuberculosis H37Rv===
===Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With inhibitor SMCS (CYS) And Phosphate From Mycobacterium tuberculosis H37Rv===
{{ABSTRACT_PUBMED_22683789}}


==Function==
[[http://www.uniprot.org/uniprot/DHAS_MYCTU DHAS_MYCTU]] Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.<ref>PMID:15752328</ref> 


==About this Structure==
==About this Structure==
[[3tz6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZ6 OCA].  
[[3tz6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZ6 OCA].  
==See Also==
*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
*[[Aspartate-semialdehyde dehydrogenase|Aspartate-semialdehyde dehydrogenase]]
==Reference==
<ref group="xtra">PMID:022683789</ref><references group="xtra"/><references/>
[[Category: Aspartate-semialdehyde dehydrogenase]]
[[Category: Aspartate-semialdehyde dehydrogenase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]

Revision as of 14:08, 10 July 2013

Template:STRUCTURE 3tz6

Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With inhibitor SMCS (CYS) And Phosphate From Mycobacterium tuberculosis H37Rv

Template:ABSTRACT PUBMED 22683789

Function

[DHAS_MYCTU] Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.[1]

About this Structure

3tz6 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

See Also

Reference

  1. Vyas R, Tewari R, Weiss MS, Karthikeyan S. Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv. Acta Crystallogr D Biol Crystallogr. 2012 Jun;68(Pt 6):671-9. doi:, 10.1107/S0907444912007330. Epub 2012 May 17. PMID:22683789 doi:10.1107/S0907444912007330
  1. ↑ Shafiani S, Sharma P, Vohra RM, Tewari R. Cloning and characterization of aspartate-beta-semialdehyde dehydrogenase from Mycobacterium tuberculosis H37 Rv. J Appl Microbiol. 2005;98(4):832-8. PMID:15752328 doi:10.1111/j.1365-2672.2004.02505.x

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