4hcq: Difference between revisions
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{{STRUCTURE_4hcq| PDB=4hcq | SCENE= }} | {{STRUCTURE_4hcq| PDB=4hcq | SCENE= }} | ||
===Crystal structure of GLMU from mycobacterium tuberculosis in complex with glucosamine-1-phosphate=== | ===Crystal structure of GLMU from mycobacterium tuberculosis in complex with glucosamine-1-phosphate=== | ||
{{ABSTRACT_PUBMED_23485416}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GLMU_MYCTU GLMU_MYCTU]] Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.<ref>PMID:19237750</ref> <ref>PMID:19121323</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[4hcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCQ OCA]. | [[4hcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCQ OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023485416</ref><references group="xtra"/><references/> | |||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Jagtap, P K.A.]] | [[Category: Jagtap, P K.A.]] | ||
