4kp6: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4kp6|  PDB=4kp6  |  SCENE=  }}
===Crystal structure of human phosphodiesterase 4B (PDE4B) in complex with a [1,3,5]triazine derivative===
{{ABSTRACT_PUBMED_23806553}}


The entry 4kp6 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN]] Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.<ref>PMID:10846163</ref> <ref>PMID:15003452</ref> 


Authors: Gewald, R., Grunwald, C., Egerland, U.
==About this Structure==
[[4kp6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KP6 OCA].  


Description: Crystal structure of human phosphodiesterase 4B (PDE4B) in complex with a [1,3,5]triazine derivative
==Reference==
<ref group="xtra">PMID:023806553</ref><references group="xtra"/><references/>
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: Homo sapiens]]
[[Category: Egerland, U.]]
[[Category: Gewald, R.]]
[[Category: Grunwald, C.]]
[[Category: Copd]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Neutrophilia]]
[[Category: Pde4 inhibitor]]
[[Category: Phosphodiesterase]]
[[Category: Triazine]]