4bcx: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4bcx|  PDB=4bcx  |  SCENE=  }}
===gamma 2 adaptin EAR domain crystal structure===


The entry 4bcx is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/AP1G2_HUMAN AP1G2_HUMAN]] May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV).<ref>PMID:9733768</ref> <ref>PMID:16867982</ref> <ref>PMID:17553870</ref>  


Authors: Juergens, M.C., Voros, J., Rautureau, G., Shepherd, D., Pye, V.E., Muldoon, J., Johnson, C.M., Ashcroft, A., Freund, S.M.V., Ferguson, N.
==About this Structure==
[[4bcx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BCX OCA].  


Description: gamma 2 adaptin EAR domain crystal structure
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Ashcroft, A.]]
[[Category: Ferguson, N.]]
[[Category: Freund, S M.V.]]
[[Category: Johnson, C M.]]
[[Category: Juergens, M C.]]
[[Category: Muldoon, J.]]
[[Category: Pye, V E.]]
[[Category: Rautureau, G.]]
[[Category: Shepherd, D.]]
[[Category: Voros, J.]]
[[Category: Gae]]
[[Category: Gamma adaptin]]
[[Category: Protein transport]]

Revision as of 15:50, 10 July 2013

Template:STRUCTURE 4bcx

gamma 2 adaptin EAR domain crystal structure

Function

[AP1G2_HUMAN] May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV).[1] [2] [3]

About this Structure

4bcx is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Takatsu H, Sakurai M, Shin HW, Murakami K, Nakayama K. Identification and characterization of novel clathrin adaptor-related proteins. J Biol Chem. 1998 Sep 18;273(38):24693-700. PMID:9733768
  2. ↑ Rost M, Mann S, Lambert C, Doring T, Thome N, Prange R. Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation. J Biol Chem. 2006 Sep 29;281(39):29297-308. Epub 2006 Jul 25. PMID:16867982 doi:M603517200
  3. ↑ Lambert C, Doring T, Prange R. Hepatitis B virus maturation is sensitive to functional inhibition of ESCRT-III, Vps4, and gamma 2-adaptin. J Virol. 2007 Sep;81(17):9050-60. Epub 2007 Jun 6. PMID:17553870 doi:JVI.00479-07

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