4fzs: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4fzs|  PDB=4fzs  |  SCENE=  }}
===Structure of human SNX1 BAR domain===


The entry 4fzs is ON HOLD until Jul 04 2014
==Function==
[[http://www.uniprot.org/uniprot/SNX1_HUMAN SNX1_HUMAN]] May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).<ref>PMID:12198132</ref> <ref>PMID:15498486</ref> <ref>PMID:17101778</ref>  


Authors: van Weering, J.R.T., Sessions, R.B., Traer, C.J., Kloer, D.P., Bhatia, V.K., Stamou, D., Hurley, J.H., Cullen, P.J.
==About this Structure==
[[4fzs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FZS OCA].  


Description: Structure of human SNX1 BAR domain
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Bhatia, V K.]]
[[Category: Cullen, P J.]]
[[Category: Hurley, J H.]]
[[Category: Kloer, D P.]]
[[Category: Sessions, R B.]]
[[Category: Stamou, D.]]
[[Category: Traer, C J.]]
[[Category: Weering, J R.T van.]]
[[Category: Bar]]
[[Category: Membrane remodeling]]
[[Category: Protein transport]]