4iru: Difference between revisions
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{{STRUCTURE_4iru| PDB=4iru | SCENE= }} | {{STRUCTURE_4iru| PDB=4iru | SCENE= }} | ||
===Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3=== | ===Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3=== | ||
{{ABSTRACT_PUBMED_23821544}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4iru]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRU OCA]. | [[4iru]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRU OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023821544</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]] | [[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]] | ||
Revision as of 04:31, 18 July 2013
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Template:ABSTRACT PUBMED 23821544
Function
[RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
About this Structure
4iru is a 6 chain structure with sequence from Homo sapiens and Legionella pneumophila subsp. pneumophila str. philadelphia 1. Full crystallographic information is available from OCA.
Reference
- Mishra AK, Del Campo CM, Collins RE, Roy CR, Lambright DG. The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-Canonical Hydrolytic Mechanism. J Biol Chem. 2013 Jul 2. PMID:23821544 doi:10.1074/jbc.M113.470625
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Legionella pneumophila subsp. pneumophila str. philadelphia 1
- Small monomeric GTPase
- Collins, R E.
- Delcampo, C M.
- Lambright, D G.
- Mishra, A K.
- Roy, C R.
- Arginine finger
- Glutamate finger
- Gtp hydrolysis
- Gtp hydrolysis activator
- Hydrolase-hydrolase complex
- Intrinsic gtpase activity
- Nucleotide binding
- P-loop motif
- Protein transport
