4gex: Difference between revisions
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{{STRUCTURE_4gex| PDB=4gex | SCENE= }} | {{STRUCTURE_4gex| PDB=4gex | SCENE= }} | ||
===Structure of a stabilised ceSAS-6 dimer, second crystal form=== | ===Structure of a stabilised ceSAS-6 dimer, second crystal form=== | ||
{{ABSTRACT_PUBMED_23798409}} | |||
==Function== | ==Function== | ||
| Line 9: | Line 10: | ||
==Reference== | ==Reference== | ||
<references group="xtra"/><references/> | <ref group="xtra">PMID:023798409</ref><references group="xtra"/><references/> | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Erat, M C.]] | [[Category: Erat, M C.]] | ||
Revision as of 04:32, 18 July 2013
Structure of a stabilised ceSAS-6 dimer, second crystal form
Template:ABSTRACT PUBMED 23798409
Function
[SAS6_CAEEL] Required for centrosome duplication. Participates in centriole assembly.[1] [2]
About this Structure
4gex is a 4 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.
Reference
- Hilbert M, Erat MC, Hachet V, Guichard P, Blank ID, Fluckiger I, Slater L, Lowe ED, Hatzopoulos GN, Steinmetz MO, Gonczy P, Vakonakis I. Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11373-8. doi:, 10.1073/pnas.1302721110. Epub 2013 Jun 24. PMID:23798409 doi:10.1073/pnas.1302721110
- ↑ Dammermann A, Muller-Reichert T, Pelletier L, Habermann B, Desai A, Oegema K. Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell. 2004 Dec;7(6):815-29. PMID:15572125 doi:S1534580704003806
- ↑ Leidel S, Delattre M, Cerutti L, Baumer K, Gonczy P. SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells. Nat Cell Biol. 2005 Feb;7(2):115-25. PMID:15665853 doi:ncb1220
