4i4b: Difference between revisions

Revision as of 04:56, 18 July 2013

[MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.

4i4b is a 2 chain structure with sequence from Pseudomonas mevalonii. Full crystallographic information is available from OCA.

Steussy CN, Critchelow CJ, Schmidt TJ, Min JK, Wrensford LV, Burgner JW, Rodwell VW, Stauffacher CV. A novel role for CoA during hydride transfer in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biochemistry. 2013 Jun 26. PMID:23802607 doi:10.1021/bi400335g

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-'''Unreleased structure'''
+{{STRUCTURE_4i4b|  PDB=4i4b  |  SCENE=  }}
+===HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA===
+{{ABSTRACT_PUBMED_23802607}}
-The entry 4i4b is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV]] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
-Authors: Stauffacher, C.V., Steussy, C.N., Critchelow, C.J., Schmidt, T., Min, J., Wrensford, L.V., Burgner, J.W., Rodwell, V.W.
+==About this Structure==
+[[4i4b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I4B OCA].
-Description: HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA
+==Reference==
+<ref group="xtra">PMID:023802607</ref><references group="xtra"/><references/>
+[[Category: Hydroxymethylglutaryl-CoA reductase]]
+[[Category: Pseudomonas mevalonii]]
+[[Category: Burgner, J W.]]
+[[Category: Critchelow, C J.]]
+[[Category: Min, J.]]
+[[Category: Rodwell, V W.]]
+[[Category: Schmidt, T.]]
+[[Category: Stauffacher, C V.]]
+[[Category: Steussy, C N.]]
+[[Category: Wrensford, L V.]]
+[[Category: Oxidoreductase]]