4k5y: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4k5y| PDB=4k5y | SCENE= }} | |||
===Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395=== | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/CRFR1_HUMAN CRFR1_HUMAN]] Receptor for corticotropin releasing factor (CRH). Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.<ref>PMID:18801728</ref> | |||
==About this Structure== | |||
[[4k5y]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5Y OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Bortolato, A.]] | |||
[[Category: Cheng, R K.Y.]] | |||
[[Category: Cooke, R M.]] | |||
[[Category: Dore, A S.]] | |||
[[Category: Hollenstein, K.]] | |||
[[Category: Jazayeri, A.]] | |||
[[Category: Kean, J.]] | |||
[[Category: Marshall, F H.]] | |||
[[Category: Weir, M.]] | |||
[[Category: 7tm]] | |||
[[Category: Family b]] | |||
[[Category: G-protein]] | |||
[[Category: Gpcr]] | |||
[[Category: Membrane]] | |||
[[Category: Membrane protein]] | |||
[[Category: Receptor]] | |||
[[Category: Signalling protein]] | |||