4lg7: Difference between revisions
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{{STRUCTURE_4lg7| PDB=4lg7 | SCENE= }} | |||
===Crystal structure MBD4 MBD domain in complex with methylated CpG DNA=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref> | |||
==About this Structure== | |||
[[4lg7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LG7 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Arrowsmith, C H.]] | |||
[[Category: Bountra, C.]] | |||
[[Category: Edwards, A M.]] | |||
[[Category: Min, J.]] | |||
[[Category: SGC, Structural Genomics Consortium.]] | |||
[[Category: Tempel, W.]] | |||
[[Category: Wernimont, A K.]] | |||
[[Category: Xu, C.]] | |||
[[Category: Hydrolase-dna complex]] | |||
[[Category: Sgc]] | |||
[[Category: Structural genomics consortium]] | |||