2m3s: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_2m3s|  PDB=2m3s  |  SCENE=  }}
===Calmodulin, i85l, f92e, h107i, l107i, a128t, m144r mutant===
{{ABSTRACT_PUBMED_23630096}}


The entry 2m3s is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/CALM_CHICK CALM_CHICK]] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.


Authors: Moroz, Y.S., Wu, Y., Cheng, H., Roder, H., Korendovych, I.V.
==About this Structure==
[[2m3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M3S OCA].  


Description: Calmodulin, i85l, f92e, h107i, l107i, a128t, m144r mutant
==Reference==
<ref group="xtra">PMID:023630096</ref><references group="xtra"/><references/>
[[Category: Gallus gallus]]
[[Category: Cheng, H.]]
[[Category: Korendovych, I V.]]
[[Category: Moroz, Y S.]]
[[Category: Roder, H.]]
[[Category: Wu, Y.]]
[[Category: Calmodulin]]
[[Category: Metal binding protein]]

Revision as of 12:58, 24 July 2013

Template:STRUCTURE 2m3s

Calmodulin, i85l, f92e, h107i, l107i, a128t, m144r mutant

Template:ABSTRACT PUBMED 23630096

Function

[CALM_CHICK] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.

About this Structure

2m3s is a 1 chain structure with sequence from Gallus gallus. Full experimental information is available from OCA.

Reference

  1. Moroz OV, Moroz YS, Wu Y, Olsen AB, Cheng H, Mack KL, McLaughlin JM, Raymond EA, Zhezherya K, Roder H, Korendovych IV. A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of nonnatural reaction. Angew Chem Int Ed Engl. 2013 Jun 10;52(24):6246-9. doi: 10.1002/anie.201302339., Epub 2013 Apr 29. PMID:23630096 doi:10.1002/anie.201302339

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