4fsa: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4fsa|  PDB=4fsa  |  SCENE=  }}
===tRNA-Guanine Transglycosylase soaked with pyridyl-alkine-substituted lin-benzoguanine ligand===


The entry 4fsa is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]


Authors: Immekus, F., Klebe, G.
==About this Structure==
 
[[4fsa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis_subsp._mobilis_zm4_=_atcc_31821 Zymomonas mobilis subsp. mobilis zm4 = atcc 31821]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FSA OCA].
Description: tRNA-Guanine Transglycosylase soaked with pyridyl-alkine-substituted lin-benzoguanine ligand
[[Category: Zymomonas mobilis subsp. mobilis zm4 = atcc 31821]]
[[Category: Immekus, F.]]
[[Category: Klebe, G.]]
[[Category: Biosynthesis]]
[[Category: Glycosyltransferase]]
[[Category: Queuosine]]
[[Category: Tim barrel]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Trna]]
[[Category: Trna processing]]

Revision as of 13:02, 24 July 2013

Template:STRUCTURE 4fsa

tRNA-Guanine Transglycosylase soaked with pyridyl-alkine-substituted lin-benzoguanine ligand

Function

[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]

About this Structure

4fsa is a 1 chain structure with sequence from Zymomonas mobilis subsp. mobilis zm4 = atcc 31821. Full crystallographic information is available from OCA.

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