4iof: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4iof|  PDB=4iof  |  SCENE=  }}
===Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE)===


The entry 4iof is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/IDE_HUMAN IDE_HUMAN]] Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.<ref>PMID:10684867</ref> <ref>PMID:17613531</ref> <ref>PMID:18986166</ref>  


Authors: McCord, L.A., Liang, W.G, Hoey, R., Dowdell, E., Koide, A., Koide, S., Tang, W.J.
==About this Structure==
[[4iof]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IOF OCA].  


Description: Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE)
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Insulysin]]
[[Category: Mus musculus]]
[[Category: Dowdell, E.]]
[[Category: Hoey, R.]]
[[Category: Koide, A.]]
[[Category: Koide, S.]]
[[Category: Liang, W G]]
[[Category: McCord, L A.]]
[[Category: Tang, W J.]]
[[Category: Hydrolase]]
[[Category: Zinc metalloprotease]]
Retrieved from "https://proteopedia.org/4iof"