4kzy: Difference between revisions
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{{Large structure}} | |||
{{STRUCTURE_4kzy| PDB=4kzy | SCENE= }} | |||
===Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/G1TN72_RABIT G1TN72_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).[HAMAP-Rule:MF_03122] [[http://www.uniprot.org/uniprot/EIF1_HUMAN EIF1_HUMAN]] Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. [[http://www.uniprot.org/uniprot/IF1AX_HUMAN IF1AX_HUMAN]] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | |||
==About this Structure== | |||
[[4kzy]] is a 36 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZY OCA]. | |||
[[Category: Homo sapiens]] | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Lomakin, I B.]] | |||
[[Category: Steitz, T A.]] | |||
[[Category: 40]] | |||
[[Category: Ribosome]] | |||
[[Category: Translation initiation]] | |||
Revision as of 13:13, 24 July 2013
Warning: this is a large structure, and loading might take a long time or not happen at all.
Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
Function
[G1TN72_RABIT] May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).[HAMAP-Rule:MF_03122] [EIF1_HUMAN] Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. [IF1AX_HUMAN] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
About this Structure
4kzy is a 36 chain structure with sequence from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA.
