4hhj: Difference between revisions
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{{STRUCTURE_4hhj| PDB=4hhj | SCENE= }} | {{STRUCTURE_4hhj| PDB=4hhj | SCENE= }} | ||
===Dengue serotype 3 RNA-dependent RNA polymerase=== | ===Dengue serotype 3 RNA-dependent RNA polymerase=== | ||
{{ABSTRACT_PUBMED_23408636}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q6DLV0_9FLAV Q6DLV0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774] | |||
==About this Structure== | ==About this Structure== | ||
[[4hhj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHJ OCA]. | [[4hhj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHJ OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023408636</ref><references group="xtra"/><references/> | |||
[[Category: Dengue virus 3]] | [[Category: Dengue virus 3]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
