4hm9: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hm9|  PDB=4hm9  |  SCENE=  }}
===Crystal structure of full-length human catenin-beta-like 1===


The entry 4hm9 is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/CTBL1_HUMAN CTBL1_HUMAN]] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.<ref>PMID:12659813</ref> <ref>PMID:18722174</ref>  


Authors: Du, Z., Huang, X., Wang, G., Wu, Y.
==About this Structure==
[[4hm9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HM9 OCA].  


Description: Crystal structure of full-length human catenin-beta-like 1
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Du, Z.]]
[[Category: Huang, X.]]
[[Category: Wang, G.]]
[[Category: Wu, Y.]]
[[Category: All alpha-helical]]
[[Category: Armadillo repeat]]
[[Category: Protein transport]]

Revision as of 05:18, 1 August 2013

Template:STRUCTURE 4hm9

Crystal structure of full-length human catenin-beta-like 1

Function

[CTBL1_HUMAN] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.[1] [2]

About this Structure

4hm9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Jabbour L, Welter JF, Kollar J, Hering TM. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Genomics. 2003 Mar;81(3):292-303. PMID:12659813
  2. ↑ Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol Cell. 2008 Aug 22;31(4):474-84. doi: 10.1016/j.molcel.2008.07.009. PMID:18722174 doi:10.1016/j.molcel.2008.07.009

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