4iz6: Difference between revisions
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{{STRUCTURE_4iz6| PDB=4iz6 | SCENE= }} | |||
===Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ENTE_ECOLI ENTE_ECOLI]] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine. | |||
==About this Structure== | |||
[[4iz6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZ6 OCA]. | |||
[[Category: Escherichia coli]] | |||
[[Category: Gulick, A M.]] | |||
[[Category: Sundlov, J A.]] | |||
[[Category: 4'phosphopantetheinylation cofactor 4'pp]] | |||
[[Category: Acyl carrier protein]] | |||
[[Category: Adenylate-forming enzyme]] | |||
[[Category: Anl superfamily]] | |||
[[Category: Chimera protein]] | |||
[[Category: Fusion protein]] | |||
[[Category: Ligase]] | |||
[[Category: Non-ribosomal peptide synthetase]] | |||
[[Category: Nrps adenylation domains and acyl carrier protein domain]] | |||
[[Category: Pseudo-translational symmetry]] | |||
Revision as of 05:19, 1 August 2013
Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry
Function
[ENTE_ECOLI] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine.
About this Structure
4iz6 is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
