3al5: Difference between revisions
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{{STRUCTURE_3al5| PDB=3al5 | SCENE= }} | {{STRUCTURE_3al5| PDB=3al5 | SCENE= }} | ||
===Crystal structure of Human TYW5=== | ===Crystal structure of Human TYW5=== | ||
{{ABSTRACT_PUBMED_20972222}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TYW5_HUMAN TYW5_HUMAN]] tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.<ref>PMID:20739293</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020972222</ref><references group="xtra"/> | <ref group="xtra">PMID:020972222</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Araiso, Y.]] | [[Category: Araiso, Y.]] | ||
