3zei: Difference between revisions

Revision as of 20:50, 7 August 2013

[CYSK_MYCTU] Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide.

3zei is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Poyraz O, Jeankumar VU, Saxena S, Schnell R, Haraldsson M, Yogeeswari P, Sriram D, Schneider G. Structure-Guided Design of Novel Thiazolidine Inhibitors of O-Acetyl Serine Sulfhydrylase from Mycobacterium tuberculosis. J Med Chem. 2013 Jul 23. PMID:23879381 doi:10.1021/jm400710k

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_3zei|  PDB=3zei  |  SCENE=  }}
+===Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor===
+{{ABSTRACT_PUBMED_23879381}}
-The entry 3zei is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/CYSK_MYCTU CYSK_MYCTU]] Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide.
-Authors: Poyraz, O., Schnell, R., Schneider, G.
+==About this Structure==
+[[3zei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEI OCA].
-Description: Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor
+==Reference==
+<ref group="xtra">PMID:023879381</ref><references group="xtra"/><references/>
+[[Category: Cysteine synthase]]
+[[Category: Mycobacterium tuberculosis]]
+[[Category: Poyraz, O.]]
+[[Category: Schneider, G.]]
+[[Category: Schnell, R.]]
+[[Category: Hydrolase]]
+[[Category: Inhibitor]]