3w0p: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3w0p|  PDB=3w0p  |  SCENE=  }}
===Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase APH(4)-Ia (D198A), ternary complex with ADP and hygromycin B===
{{ABSTRACT_PUBMED_23747390}}


The entry 3w0p is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/KHYB_ECOLX KHYB_ECOLX]] The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation. Only phosphorylates hygromycin and closely related compounds such as demethyl analogs and destomycin.


Authors: Iino, D., Takakura, Y., Fukano, K., Sasaki, Y., Hoshino, T., Ohsawa, K., Nakamura, A., Yajima, S.
==About this Structure==
[[3w0p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0P OCA].  


Description: Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase APH(4)-Ia (D198A), ternary complex with ATP and hygromycin B
==Reference==
<ref group="xtra">PMID:023747390</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Hygromycin B 4-O-kinase]]
[[Category: Fukano, K.]]
[[Category: Hoshino, T.]]
[[Category: Iino, D.]]
[[Category: Nakamura, A.]]
[[Category: Ohsawa, K.]]
[[Category: Sasaki, Y.]]
[[Category: Takakura, Y.]]
[[Category: Yajima, S.]]
[[Category: Phosphotransferase]]
[[Category: Transferase-antibiotic complex]]