4gi0: Difference between revisions
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{{STRUCTURE_4gi0| PDB=4gi0 | SCENE= }} | {{STRUCTURE_4gi0| PDB=4gi0 | SCENE= }} | ||
===Crystal structure of CD23 lectin domain mutant E249A=== | ===Crystal structure of CD23 lectin domain mutant E249A=== | ||
{{ABSTRACT_PUBMED_23775083}} | |||
==Function== | ==Function== | ||
| Line 7: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[4gi0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GI0 OCA]. | [[4gi0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GI0 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023775083</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Dhaliwal, B.]] | [[Category: Dhaliwal, B.]] | ||
Revision as of 06:34, 14 August 2013
Crystal structure of CD23 lectin domain mutant E249A
Template:ABSTRACT PUBMED 23775083
Function
[FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
About this Structure
4gi0 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yuan D, Keeble AH, Hibbert RG, Fabiane S, Gould HJ, McDonnell JM, Beavil AJ, Sutton BJ, Dhaliwal B. Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J Biol Chem. 2013 Jul 26;288(30):21667-77. doi: 10.1074/jbc.M113.480657. Epub, 2013 Jun 17. PMID:23775083 doi:10.1074/jbc.M113.480657
