3vl1: Difference between revisions
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{{STRUCTURE_3vl1| PDB=3vl1 | SCENE= }} | {{STRUCTURE_3vl1| PDB=3vl1 | SCENE= }} | ||
===Crystal structure of yeast Rpn14=== | ===Crystal structure of yeast Rpn14=== | ||
{{ABSTRACT_PUBMED_22691779}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RPN14_YEAST RPN14_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Is not a genuine component of the 26S proteasome, but an auxiliary factor that interacts with the proteasomal ATPase of 19S regulatory particle (RP). Acts as a chaperone which regulates the highly structured assembly of the 19S regulatory particle. Involved in the substrate specificity of the 26S proteasome and is especially involved in the degradation of ubiquitinated GCN4. May contribute to the stability of the 26S proteasome in some stress conditions.<ref>PMID:17499717</ref> <ref>PMID:19412159</ref> <ref>PMID:19446322</ref> <ref>PMID:19446323</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3vl1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3vl1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VL1 OCA]. | ||
==See Also== | ==See Also== | ||
*[[Proteasome|Proteasome]] | *[[Proteasome|Proteasome]] | ||
[[Category: Saccharomyces cerevisiae]] | |||
==Reference== | |||
<ref group="xtra">PMID:022691779</ref><references group="xtra"/><references/> | |||
[[Category: Saccharomyces cerevisiae s288c]] | |||
[[Category: Kato, K.]] | [[Category: Kato, K.]] | ||
[[Category: Kim, S.]] | [[Category: Kim, S.]] | ||
