4bb7: Difference between revisions
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{{STRUCTURE_4bb7| PDB=4bb7 | SCENE= }} | |||
===Crystal structure of the yeast Rsc2 BAH domain=== | |||
{{ABSTRACT_PUBMED_23907388}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/RSC2_YEAST RSC2_YEAST]] Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is involved in meiotic sporulation through regulating IME2 expression, and is also essential for 2-micron plasmid maintenance and for normal REP1 protein localization.<ref>PMID:12024034</ref> <ref>PMID:8980231</ref> <ref>PMID:10025404</ref> <ref>PMID:10329629</ref> <ref>PMID:12702296</ref> <ref>PMID:12183366</ref> <ref>PMID:12072455</ref> <ref>PMID:12697820</ref> | |||
==About this Structure== | |||
[[4bb7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BB7 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023907388</ref><references group="xtra"/><references/> | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Chambers, A L.]] | |||
[[Category: Downs, J A.]] | |||
[[Category: Oliver, A W.]] | |||
[[Category: Pearl, L H.]] | |||
[[Category: Dna binding]] | |||
[[Category: Transcription]] | |||