2m85: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_2m85|  PDB=2m85  |  SCENE=  }}
===PHD Domain from Human SHPRH===


The entry 2m85 is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/SHPRH_HUMAN SHPRH_HUMAN]] E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.<ref>PMID:17130289</ref> <ref>PMID:17108083</ref> <ref>PMID:18719106</ref>  


Authors: Machado, L.E.S.F., Pustovalova, Y., Pozhidaeva, A., Almeida, F.C.L., Bezsonova, I., Korzhnev, D.M.
==About this Structure==
[[2m85]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M85 OCA].  


Description: PHD Domain from Human SHPRH
==Reference==
<ref group="xtra">PMID:023907177</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Almeida, F C.L.]]
[[Category: Bezsonova, I.]]
[[Category: Korzhnev, D M.]]
[[Category: Machado, L E.S F.]]
[[Category: Pozhidaeva, A.]]
[[Category: Pustovalova, Y.]]
[[Category: Helicase]]
[[Category: Histone linker]]
[[Category: Hydrolase]]
[[Category: Ligase]]
[[Category: Phd finger]]
[[Category: Ring finger]]
[[Category: Shprh]]
[[Category: Snf2]]