Sandbox 127: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 50: | Line 50: | ||
residues in PBP2a; specifically | residues in PBP2a; specifically | ||
<scene name='37/372724/Medicine_interaction/2'>Tyr446 and Met641</scene>.The | <scene name='37/372724/Medicine_interaction/2'>Tyr446 and Met641</scene>.The | ||
<scene name='37/372724/Medicine_interaction/1'> medicine</scene> shown as colors of the atom types ([[CPK]]) is able to more efficiently react with | <scene name='37/372724/Medicine_interaction/1'> medicine</scene> shown as colors of the atom types ([[CPK]]) is able to more efficiently react with <scene name='37/372724/R2_interaction/9'>Ser403</scene> and therefore inhibit the activity of pbp2a as a result of ceftobiprole <scene name='37/372724/R2_interaction/8'>tighter binding</scene> to pbp2a. Unlike penicillin, this results in inhibition of PBP2a. | ||
<scene name='37/372724/R2_interaction/9'>Ser403</scene> | |||
