2ma2: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Solution structure of RasGRP2 EF hands bound to calcium===

~~The entry 2ma2 is ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/GRP2_HUMAN GRP2_HUMAN]] Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.<ref>PMID:10918068</ref> <ref>PMID:14702343</ref> <ref>PMID:17702895</ref> <ref>PMID:17576779</ref>

~~Authors~~: ~~Kuriyan, J~~.~~, Iwig, J~~.~~, Vercoulen, Y~~.~~, Das, R., Barros, T., Limnander, A., Che, Y~~.~~, Pelton, J~~.~~, Wemmer, D~~.~~, Roose, J~~.

==About this Structure==

[[2ma2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MA2 OCA].

~~Description~~: ~~Solution structure of RasGRP2 EF hands bound to calcium~~

==Reference==

[[Category: Homo sapiens]]

[[Category: Barros, T.]]

[[Category: Che, Y.]]

[[Category: Das, R.]]

[[Category: Iwig, J.]]

[[Category: Kuriyan, J.]]

[[Category: Limnander, A.]]

[[Category: Pelton, J.]]

[[Category: Roose, J.]]

[[Category: Vercoulen, Y.]]

[[Category: Wemmer, D.]]

[[Category: Calcium-binding protein]]

[[Category: Ef hand]]

[[Category: Protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_2ma2|  PDB=2ma2  |  SCENE=  }}
+===Solution structure of RasGRP2 EF hands bound to calcium===
+{{ABSTRACT_PUBMED_23908768}}
-The entry 2ma2 is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/GRP2_HUMAN GRP2_HUMAN]] Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.<ref>PMID:10918068</ref> <ref>PMID:14702343</ref> <ref>PMID:17702895</ref> <ref>PMID:17576779</ref>
-Authors: Kuriyan, J., Iwig, J., Vercoulen, Y., Das, R., Barros, T., Limnander, A., Che, Y., Pelton, J., Wemmer, D., Roose, J.
+==About this Structure==
+[[2ma2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MA2 OCA].
-Description: Solution structure of RasGRP2 EF hands bound to calcium
+==Reference==
+<ref group="xtra">PMID:023908768</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Barros, T.]]
+[[Category: Che, Y.]]
+[[Category: Das, R.]]
+[[Category: Iwig, J.]]
+[[Category: Kuriyan, J.]]
+[[Category: Limnander, A.]]
+[[Category: Pelton, J.]]
+[[Category: Roose, J.]]
+[[Category: Vercoulen, Y.]]
+[[Category: Wemmer, D.]]
+[[Category: Calcium-binding protein]]
+[[Category: Ef hand]]
+[[Category: Protein]]