4jb8: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jb8|  PDB=4jb8  |  SCENE=  }}
===Caspase-7 in Complex with DARPin C7_16===
{{ABSTRACT_PUBMED_23868333}}


The entry 4jb8 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.


Authors: Fluetsch, A., Seeger, M.A., Gruetter, M.G.
==About this Structure==
[[4jb8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JB8 OCA].  


Description: Caspase-7 in Complex with DARPin C7_16
==Reference==
<ref group="xtra">PMID:023868333</ref><references group="xtra"/><references/>
[[Category: Caspase-7]]
[[Category: Homo sapiens]]
[[Category: Synthetic construct]]
[[Category: Fluetsch, A.]]
[[Category: Gruetter, M G.]]
[[Category: Seeger, M A.]]
[[Category: Complex structure]]
[[Category: Hydrolase-de novo protein complex]]
[[Category: Selected darpin c7_16]]