4bwx: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4bwx|  PDB=4bwx  |  SCENE=  }}
===Structure of Neurospora crassa PAN3 pseudokinase mutant===
{{ABSTRACT_PUBMED_23932717}}


The entry 4bwx is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/PAN3_NEUCR PAN3_NEUCR]] Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex involved in cytoplasmic mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein pab-1. Deadenylation of the 3'-tail to a length that is too short to bind pab-1 induces mRNA decay. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. pan-3 acts as a positive regulator for PAN activity, recruiting pan-2 to mRNA via its interaction with pab-1 (By similarity).


Authors: Christie, M., Boland, A., Huntzinger, E., Weichenrieder, O., Izaurralde, E.
==About this Structure==
[[4bwx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neurospora_crassa Neurospora crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BWX OCA].  


Description: Structure of Neurospora crassa PAN3 pseudokinase mutant
==Reference==
<ref group="xtra">PMID:023932717</ref><references group="xtra"/><references/>
[[Category: Neurospora crassa]]
[[Category: Boland, A.]]
[[Category: Christie, M.]]
[[Category: Huntzinger, E.]]
[[Category: Izaurralde, E.]]
[[Category: Weichenrieder, O.]]
[[Category: Deadenylase]]
[[Category: Gene regulation]]
[[Category: Mirna]]
[[Category: Mrna decay]]
[[Category: Pan2]]