4ky8: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4ky8|  PDB=4ky8  |  SCENE=  }}
===Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, methotrexate, FdUMP and 4-((2-amino-6-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)thio)-2-chlorophenyl)-L-glutamic acid===
{{ABSTRACT_PUBMED_23927969}}


The entry 4ky8 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/Q5CGA3_CRYHO Q5CGA3_CRYHO]] Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (By similarity).[PIRNR:PIRNR000389]


Authors: Kumar, V.P., Anderson, K.S.
==About this Structure==
[[4ky8]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KY8 OCA].  


Description: Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, methotrexate, FdUMP and 4-((2-amino-6-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)thio)-2-chlorophenyl)-L-glutamic acid
==Reference==
<ref group="xtra">PMID:023927969</ref><references group="xtra"/><references/>
[[Category: Cryptosporidium hominis]]
[[Category: Anderson, K S.]]
[[Category: Kumar, V P.]]
[[Category: Bifunctional enzyme]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-inhibitor complex]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4ky8"