4kg3: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4kg3|  PDB=4kg3  |  SCENE=  }}
===Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg (E153Q mutation)===
{{ABSTRACT_PUBMED_23911090}}


The entry 4kg3 is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/DCP2_YEAST DCP2_YEAST]] Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Decapping is the major pathway of mRNA degradation in yeast. It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body.<ref>PMID:10508173</ref> <ref>PMID:11139489</ref> <ref>PMID:11741542</ref> <ref>PMID:12554866</ref>  


Authors: Aglietti, R.A., Floor, S.N., Gross, J.D.
==About this Structure==
[[4kg3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KG3 OCA].  


Description: Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg (E153Q mutation)
==Reference==
<ref group="xtra">PMID:023911090</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae s288c]]
[[Category: Aglietti, R A.]]
[[Category: Floor, S N.]]
[[Category: Gross, J D.]]
[[Category: Hydrolase]]
[[Category: Mrna decapping]]
[[Category: Mrna decay]]
[[Category: Nudix]]