Adaptin: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) New page: == Your Heading Here (maybe something like 'Structure') == <StructureSection load='1dq8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry 1dq8)' scene=''> Ada... |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='1dq8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1dq8]])' scene=''> | <StructureSection load='1dq8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1dq8]])' scene=''> | ||
Adaptin (AP) are proteins which mediate the formation of vescicles by clathrin-coated pits. The AP complex is a hetertetramer composed of 2 large AP: APalpha or APgamma and APbeta, a medium-size AP: APmu and small AP: APsigma. AP complexes connect proteins and lipids to clathrin budding sites. There are different AP complexes in mammals. | '''Adaptin''' (AP) are proteins which mediate the formation of vescicles by clathrin-coated pits. The AP complex is a hetertetramer composed of 2 large AP: APalpha or APgamma and APbeta, a medium-size AP: APmu and small AP: APsigma. AP complexes connect proteins and lipids to clathrin budding sites. There are different AP complexes in mammals. | ||
'''AP-α''' | |||
[[1b9x]], [[1qts]] – mAP appendage domain – mouse<br /> | [[1b9x]], [[1qts]] – mAP appendage domain – mouse<br /> | ||
[[1qtp]] – mAP appendage domain (mutant)<br /> | [[1qtp]] – mAP appendage domain (mutant)<br /> | ||
| Line 12: | Line 12: | ||
[[3hs8]] – mAP appendage domain + intersectin peptide<br /> | [[3hs8]] – mAP appendage domain + intersectin peptide<br /> | ||
'''AP-β''' | |||
[[1e42]] - hAP appendage domain - human<br /> | [[1e42]] - hAP appendage domain - human<br /> | ||
[[2g30]] – hAP appendage domain + ARH peptide<br /> | [[2g30]] – hAP appendage domain + ARH peptide<br /> | ||
| Line 20: | Line 21: | ||
[[3hs9]] – hAP appendage domain + intersectin peptide<br /> | [[3hs9]] – hAP appendage domain + intersectin peptide<br /> | ||
'''AP-γ''' | |||
[[1iu1]], [[2e9g]], [[4bcx]] – hAP ear domain<br /> | [[1iu1]], [[2e9g]], [[4bcx]] – hAP ear domain<br /> | ||
[[2ymt]] – hAP ear domain + peptide<br /> | [[2ymt]] – hAP ear domain + peptide<br /> | ||
| Line 27: | Line 29: | ||
[[1gyv]], [[1gyw]], [[3zy7]] – mAP appendage domain (mutant)<br /> | [[1gyv]], [[1gyw]], [[3zy7]] – mAP appendage domain (mutant)<br /> | ||
'''AP-δ''' | |||
[[4afi]] – hAP/vesicle-associated membrane protein 7<br /> | [[4afi]] – hAP/vesicle-associated membrane protein 7<br /> | ||
'''AP-μ''' | |||
[[1bw8]], [[1i31]] – rAP + EGFR peptide<br /> | [[1bw8]], [[1i31]] – rAP + EGFR peptide<br /> | ||
[[1bxx]] – rAP + TGN38 peptide<br /> | [[1bxx]] – rAP + TGN38 peptide<br /> | ||
