Catalase: Difference between revisions
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{{STRUCTURE_1gge| PDB=1gge | SIZE=400| SCENE= |right|CAPTION=E. coli catalase Hpii tetramer showing the heme group, [[1gge]] }} | {{STRUCTURE_1gge| PDB=1gge | SIZE=400| SCENE= |right|CAPTION=E. coli catalase Hpii tetramer showing the heme group, [[1gge]] }} | ||
'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). | '''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity. | ||
__NOTOC__ | __NOTOC__ | ||
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[[1jkv]] - LpPCAT-Mn + N3 | [[1jkv]] - LpPCAT-Mn + N3 | ||
===Catalase-phenol oxidase=== | |||
[[4aue]], [[4aul]], [[4aum]], [[4aun]], [[4b2y]], [[4b31]], [[4b40]], [[4b5k]] - CATPO - ''Scytalidium thermophilum'' <br /> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
